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Cell and DNA Physics
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Thermal Properties of
     Complex Heterogeneous
     Biological Systems

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Interaction of Nanoparticles
     with DNA

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Organism Protection Systems
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DEPARTMENT OF BIOLOGICAL SYSTEM
PHYSICS


HEAD
Dr. Jamlet Monaselidze, Doc. Sc.
     Tel: +(995 32) 232 68 58
     Fax: +(995 32) 239 14 94
     E-mail: j.monaselidze@aiphysics.ge
                   jamlet_monaselidze@yahoo.com

Mail:
Andronikashvili Institute of Physics
6, Tamarashvili St., 0186 Tbilisi
Georgia
A short history of the department.    Main research fields.

During many years, at the Department of Physics of Biological Systems, we have been studying of such dynamical, stuctural and funcional changes of human, animal and fague genomes, which are conditioned by influence of heavy metal ions, carcinogens, toxic agents and bioregulators. We also study role of water in stability of biological macro-
molecules and influence of water on physical and chemical characteristics of cells of different origin. The obtained results give a possibility to reveal new law of nature regarding stability of genom and vital functions of the studied cells. New ideas, original laboratory equipment and methods created at our department with intensive collaboration with leading European and US laboratories play an important role in revealing of these laws. In 1964-1965, the first high-sensitive microcalorimeter was created for study solutions of biological polymers (P. Privalov, J. Monaselidze). Different modified models for study of complex biological systems (cell suspensions, whole tissues) were created in 1970-2011 (J. Monaselidze, N. Bakradze, E. Kiziria, G. Majagaladze). The following equipments were also created at ourt department: a modified capilar electrophoresis (N. Tsibakhashvili, L. Mosulishvili), a modified atom spectrophotometer (US Patent 2003, A. Rcheulishvili), and two types of glow discharge atom-emission spectrophotometers (V. Bregadze). A new biochip technology is created in our department (2009-2011) for rapid diagnosis of viral and bacterial diseases as well as for identification of microorganisms, causing adverse environmental conditions
(N. Sapojnikova, T. Kartvelishvili, N. Asatiani).
Five groups work at the department in fields of molecular biophysics, molecular biology and biochemists.